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Table 3 Associations between selected risk factors for breast cancer andmammograms classified according to four methods

From: Percentage density, Wolfe's and Tabár's mammographic patterns: agreement and association with risk factors for breast cancer

Characteristic Upper quartile High-risk patterns Reader NB
  Reader GM ≥ 28.3% Reader GU ≥ 19.0% Wolfe Tabár
Age at screening     
   <60 years 1.00 1.00 1.00 1.00
   60–64 years 0.65 0.74 0.64 0.79
   65+ years 0.52 0.53 0.59 0.64
P for trend <0.01 <0.01 <0.01 <0.03
Age at menarche     
   <13 years 1.00 1.00 1.00 1.00
   13–14 years 1.24 1.28 1.26 1.36
   14+ years 0.90 1.04 0.81 0.76
P for trend 0.99 0.50 0.67 0.70
Age at menopause     
   <48 years 1.00 1.00 1.00 1.00
   48–50 years 0.80 0.85 0.90 0.87
   51+ years 0.95 1.14 1.38 1.11
P for trend 0.83 0.47 0.06 0.61
Age at first birth     
   <20 years 1.00 1.00 1.00 1.00
   20–24 years 0.99 1.15 1.41 1.14
   25+ years 1.30 1.66 1.67 1.40
P for trend 0.27 0.07 0.05 0.15
Number of children     
   0 1.00 1.00 1.00 1.00
   1 1.14 1.54 1.61 1.16
   2 0.52 0.87 0.87 0.40
   3 0.51 0.60 0.90 0.37
   4+ 0.18 0.23 0.41 0.21
P for trend – all <0.0001 <0.0001 <0.0001 <0.0001
Body mass index     
   <25 1.00 1.00 1.00 1.00
   25–30 0.39 0.48 0.53 0.81
   >30 0.15 0.19 0.24 0.36
P for trend <0.0001 <0.0001 <0.0001 <0.0001
  1. Multivariate odds ratios have been adjusted for age at screening, age at menarche, age at menopause, number of children, age at first birth, and body mass index where applicable. Total numbers in the multivariate models may vary slightly owing to missing values for covariates.