Table 1 Characteristics of the study participants overall and with mammograms classified as high-risk density patterns
Characteristic | All women | Quantitative Reader GM | Reader GU/GM | Reader GU | Pattern Reader NB | |
|---|---|---|---|---|---|---|
n = 987 | Upper quartile ≥ 28.3% (n = 249) | Upper quartile ≥ 21.0% (n = 246) | Upper quartile ≥ 19.0% (n = 247) | Wolfe P2, DY (n = 462) | Tabár IV, V (n = 233) | |
Age (years) at screening, mean ± SD | 61.4 ± 4.5 | 60.4 ± 4.4 | 60.3 ± 4.5 | 60.3 ± 4.5 | 60.8 ± 4.6 | 60.6 ± 4.5 |
Age (years) at menarche, mean ± SD | 13.3 ± 1.4 | 13.4 ± 1.3 | 13.4 ± 1.3 | 13.4 ± 1.3 | 13.3 ± 1.3 | 13.4 ± 1.3 |
Age (years) at menopause, mean ± SD | 48.5 ± 5.1 | 48.5 ± 4.9 | 48.8 ± 4.8 | 48.8 ± 4.7 | 48.8 ± 4.9 | 48.7 ± 4.8 |
Parous (%) | 92.6 | 89.2 | 88.6 | 87.5 | 89.4 | 88.0 |
Age (years) at first birth/pregnancy, mean ± SD | 22.9 ± 3.7 | 23.9 ± 4.3 | 24.1 ± 4.3 | 24.1 ± 4.3 | 23.4 ± 3.9 | 23.9 ± 4.4 |
Number of children, mean ± SD | 2.6 ± 1.4 | 2.1 ± 1.2 | 2.1 ± 1.1 | 2.0 ± 1.2 | 2.3 ± 1.3 | 2.1 ± 1.2 |
Body mass index, mean ± SD | 27.4 ± 4.8 | 24.9 ± 3.6 | 25.1 ± 3.7 | 25.1 ± 3.8 | 26.0 ± 4.0 | 25.9 ± 3.8 |
Wolfe high-risk patterns (P2, DY) (%) | 46.8 | 95.6 | 96.3 | 96.4 | - | 99.1 |
Tabár high-risk patterns (IV, V) (%) | 23.6 | 60.6 | 66.3 | 67.2 | 50 | - |
Reader GM | ||||||
Median density, % (range) | 14.5 (0–88.4) | - | 41.1 (9.4–88.4) | 39.4 (7.6–88.4) | 28.6 (1.9–88.4) | 34.9 (1.9–88.4) |
Reader GU | ||||||
Median density, % (range) | 9.6 (0–69.2) | 26.6 (0.6–69.2) | 27.7 (0.6–69.2) | - | 19.4 (0.6–69.2) | 25.2 (3.5–69.2) |
Readers GU and GM | ||||||
Median density, % (range) | 29.5 (3.9–73.8) | - | 30.5 (18.4–73.8) | 21.7 (2.1–73.8) | 28.1 (3.6–73.8) |