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Figure 1 | Breast Cancer Research

Figure 1

From: Expression of hypoxia-inducible factor 1 alpha and its downstream targets in fibroepithelial tumors of the breast

Figure 1

Examples of immunostaining for hypoxia-inducible factor 1 alpha (HIF-1α) and carbonic anhydrase IX (CAIX) in breast phyllodes tumors. (a) Malignant phyllodes tumor with stromal CAIX expression. (b) Same tumor as (a) with topographically overlapping HIF-1α overexpression. (c) Benign phyllodes tumor with CAIX-positive staining epithelium. (d) Borderline phyllodes tumor with HIF-1α overexpression in normal appearing epithelium and in subepithelial stroma.

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