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Table 1 Comparison of subjects carrying BRCA mutations

From: Changes in body weight and the risk of breast cancer in BRCA1 and BRCA2mutation carriers

Variable Control subjects (n = 1,073) Case subjects (n = 1,073) P a
Age (years) at interview, no. (%)    
   ≤ 30 17 (1.6) 26 (2.4)  
   31–40 219 (20.4) 242 (22.5)  
   41–50 415 (38.7) 386 (36.0)  
   51–60 277 (25.8) 264 (24.6)  
   ≥ 61 145 (13.5) 155 (14.5) 0.32
Age (years) at interview, mean (SD) 47.9 (10.6) 48.6 (10.6) 0.25
Date of birth, mean year 1951.8 1951.2 0.14
Year of interview, mean (range) 1999.7 (1995–2004) 1999.8 (1999–2004) 0.18
Age (years) at diagnosis of breast cancer, no. (%)    
   ≤ 30 NA 107 (10.0)  
   31–40   478 (44.5)  
   41–50   371 (34.5)  
   ≥ 51   117 (10.9)  
Age (years) at diagnosis of breast cancer, mean (SD)   39.8 (8.3)  
Mutation, %    
   BRCA1 74.3 74.3  
   BRCA2 25.7 25.7  
Parity    
   No. (%) parous 844 (79.6) 879 (82.8) 0.06
   Parity, mean (SD) 1.9 (1.4) 1.9 (1.3) 0.18
No. (%) who ever used oral contraceptives 662 (62.6) 710 (66.8) 0.04
No. (%) who ever smoked 465 (43.3) 471 (43.9) 0.79
   Country of residence at time of testing, no. (%)    
   Canada 420 (39.1) 420 (39.1)  
   Israel 20 (1.9) 20 (1.9)  
   UK 8 (0.8) 8 (0.8)  
   Poland 189 (17.6) 189 (17.6)  
   USA 436 (40.6) 436 (40.6)  
  1. aAll P values are univariate and were derived using Student's t-test for continuous variables and the χ2 test for categorical variables. NA, not applicable; SD, standard deviation.