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Table 6 Univariate and multivariate analysis of factors predicting postrelapse survival

From: Phosphorylation of estrogen receptor α serine 167 is predictive of response to endocrine therapy and increases postrelapse survival in metastatic breast cancer

 

Univariate

Multivariate

Factor

P

RR

95% CI

P

RR

95% CI

Age

0.67

0.882

0.494–1.576

   

Tumor size

0.21

1.483

0.797–2.759

   

Lymph node status

0.40

0.746

0.376–1.479

   

Histological grade

0.20

0.542

0.213–1.382

   

HER2

0.0033*

0.340

0.166–0.699

   

ER-α (1D5)

0.0009*

2.924

1.550–5.515

0.0076*

2.465

1.271–4.781

ER-α Ser118

0.36

1.308

0.732–2.340

   

ER-α Ser167

0.035*

1.890

1.045–3.420

0.19

1.536

0.841–2.900

ER-β1

0.37

1.355

0.697–2.635

   

ER-βcx/β2

0.10

1.627

0.905–2.926

   

PR (636)

0.0012*

2.796

1.498–5.220

   

PRA

0.03*

2.182

1.202–3.960

   

PRB

0.013*

2.157

1.177–3.951

0.24

1.499

0.763–2.945

  1. CI, confidence interval; ER, estrogen receptor; PR, progesterone receptor; RR, relative risk. *P < 0.05.