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Table 2 Correlations between immunohistochemistry scores for expression and phosphorylation of hormone receptors in primary breast tumors

From: Phosphorylation of estrogen receptor α serine 167 is predictive of response to endocrine therapy and increases postrelapse survival in metastatic breast cancer

Receptor ER-α (1D5) ER-α Ser118 ER-α Ser167 ER-β1 ER-βcx/β2 PR (636) PRA
ER-α Ser118 +0.224a       
  0.055b       
ER-α Ser167 +0.140 +0.556      
  0.23 <0.0001*      
ER-β1 +0.039 +0.589 +0.417     
  0.74 <0.0001* 0.0003*     
ER-βcx/β2 +0.009 +0.640 +0.518 +0.693    
  0.94 <0.0001* <0.0001* <0.0001*    
PR (636) +0.446 +0.032 +0.011 +0.004 -0.015   
  0.0001* 0.78 0.92 0.97 0.90   
PRA +0.256 +0.463 +0.394 +0.203 +0.378 +0.500  
  0.028* <0.0001* 0.0007* 0.081 0.0011* <0.0001*  
PRB +0.187 +0.211 +0.149 +0.206 +0.325 +0.553 +0.526
  0.11 0.070 0.20 0.077 0.0052* <0.0001* <0.0001*
  1. aSpearman correlation coefficient; bP, Spearman rank correlation test. * P <0.05.
  2. ER, estrogen receptor; PR(A,B), progresterone receptor (A,B).
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Breast Cancer Research

ISSN: 1465-542X

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