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Table 1 Combination index values induced by sequential treatments

From: Addition of 5-fluorouracil to doxorubicin-paclitaxel sequence increases caspase-dependent apoptosis in breast cancer cell lines

  

MCF-7

BRC-230

  

CI value at inhibition of

CI value at inhibition of

Drug combination

Combination ratio

75%

90%

95%

75%

90%

95%

Dox→Pacl

1:1

0.3

0.3

0.4

0.1

0.2

0.2

Dox→Pacl→48-h washout→5-FU

1:1:10

0.0005

0.002

0.005

0.002

0.007

0.02

  1. 5-FU, 5-fluorouracil; CI, combination index; Dox, doxorubicin; Pacl, paclitaxel.
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Breast Cancer Research

ISSN: 1465-542X

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