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Table 1 Randomized controlled trials of combination estrogen plus progestin postmenopausal hormone therapy and recurrence of breast cancer

From: Menopausal hormone therapy after breast cancer

Author [ref.] Year Number of patients randomized Number of patients with follow up Duration of follow up Number of recurrences (hormone therapy/control) RR (95% CI)
Marsden et al. [23] 2000 100 83 6 months 2/1 2
Holmberg and Anderson [15] 2004 434 345 2.1 years 26/7 3.3 (1.5–7.4)
von Schoultz and Rutqvist [14] 2005 378 359 4.1 years 11/13 0.82 (0.35–1.9)
  1. CI, confidence interval; RR, relative risk.