Table 1 Randomized controlled trials of combination estrogen plus progestin postmenopausal hormone therapy and recurrence of breast cancer
Author [ref.] | Year | Number of patients randomized | Number of patients with follow up | Duration of follow up | Number of recurrences (hormone therapy/control) | RR (95% CI) |
|---|---|---|---|---|---|---|
Marsden et al. [23] | 2000 | 100 | 83 | 6 months | 2/1 | 2 |
Holmberg and Anderson [15] | 2004 | 434 | 345 | 2.1 years | 26/7 | 3.3 (1.5–7.4) |
von Schoultz and Rutqvist [14] | 2005 | 378 | 359 | 4.1 years | 11/13 | 0.82 (0.35–1.9) |