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Table 3 Details of the identified 37 predictive genes

From: Early detection of breast cancer based on gene-expression patterns in peripheral blood cells

Accession no. Gene similarity Putative cellular function Position ID Scorea
BC000514 Ribosomal protein L13a Ribosome production 19AM 0.8377
BC007512 Ribosomal protein L18a Ribosome production 31AJ 0.7321
BC019093 Guanine nucleotide binding protein, beta polypeptide 2-like; RACKs (receptors for activated C kinase) Protein translation 12AM 0.6972
BC009696 Interferon induced transmembrane protein 2 Cell – environment interaction, Immune response 12Q -0.6962
BC047681 S100 calcium binding protein A9 (Calgranulin B) Defence; inhibition of casein kinase II 31J -0.6444
BC066901 H3 histone, family 3B (H3.3B) Chromatin remodelling 5AK -0.6394
BC034149 Ribosomal protein S3 Ribosome production 23V 0.639
AK026634 Highly similar to HUMTI227HC, mRNA for TI-227H - 21AH 0.627
BC047681 S100 calcium binding protein A9 (Calgranulin B) Defence; inhibition of casein kinase II 24AQ -0.627
BC001126 Ribosomal protein S14 Ribosome production 28T 0.6231
NM_000980 Ribosomal protein L18a Ribosome production 31AF 0.6215
AY495316 Cytochrome c oxidase subunit, COX 1 Mitochondrial electron transport chain 15AK 0.6112
NM_001016 Ribosomal protein S12 Ribosome production 22S 0.6102
- - - 20AG 0.5839
BC016378 Ribosomal protein S11 Ribosome production 8S 0.5827
AY495316 Cytochrome c oxidase subunit, COX 1 Mitochondrial electron transport chain 27AG 0.5729
AF077043 Ribosomal protein L36 Ribosome production 3AR 0.5699
AF346981 Mitochondrial 16S rRNA Ribosome production 25P 0.5507
BC013857 H3 histone, family 3A Chromatin remodelling 3T -0.5496
M22146 Ribosomal protein S4 Ribosome production 31U 0.5176
BC016857 Ferritin, heavy polypeptide 1 Iron storage; defence against ROS 6N -0.5134
BC053370 Ribosomal protein SA Ribosome production 2G 0.5113
BC010165 Ribosomal protein S2 Ribosome production 2V 0.5071
BC009689 Cyclin D-type binding protein E2F-mediated transcription 21O 0.4978
BC018641 Eukaryotic translation elongation factor 1α (eEF1A) Protein translation 4AA 0.4974
D87735 Ribosomal protein L14 Ribosome production 19H 0.486
- - - 6AQ 0.4837
BC016857 Ferritin, heavy polypeptide 1 Iron storage; defence against ROS 3AB -0.481
BC012146 Ribosomal protein L3 Ribosome production 32AM 0.4776
BC001126 Ribosomal protein S14 Ribosome production 25R 0.4759
BC006784 Ribosomal protein S14 Ribosome production 24AJ 0.4695
J03223 Human secretory granule proteoglycan peptide core Defence (may neutralize hydrolytic enzymes) 11H -0.4681
AY147037 Myeloid/lymphoid or mixed-lineage leukemia 5 cDNA Chromatin remodeling and cellular growth suppression 30AP 0.4669
CD246392, EST Agencourt_14095501 NIH_MGC_172 cDNA - 8AK 0.4666
AY339570 Cytochrome c oxidase subunit, COX 1 Mitochondrial electron transport chain 2E 0.4662
U43701 Human ribosomal protein L23a Ribosome production 8G 0.4629
AY495252 Mitochondrial 16S rRNA Ribosome production 8AF 0.4625
  1. The position of genes in the array is shown as well as their scores, the accession number of sequences in public databases that match them, and their known or putative cellular function. aThe score is a shrunken t-statistic for comparing breast-cancer class to non-breast-cancer class. A positive score means that expression was greater in the noncancer sample than the cancer sample; a negative score means that expression was greater in the cancer sample than the noncancer sample. -, no information available; ROS, reactive oxygen species.