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Table 3 Details of the identified 37 predictive genes

From: Early detection of breast cancer based on gene-expression patterns in peripheral blood cells

Accession no.

Gene similarity

Putative cellular function

Position ID

Scorea

BC000514

Ribosomal protein L13a

Ribosome production

19AM

0.8377

BC007512

Ribosomal protein L18a

Ribosome production

31AJ

0.7321

BC019093

Guanine nucleotide binding protein, beta polypeptide 2-like; RACKs (receptors for activated C kinase)

Protein translation

12AM

0.6972

BC009696

Interferon induced transmembrane protein 2

Cell – environment interaction, Immune response

12Q

-0.6962

BC047681

S100 calcium binding protein A9 (Calgranulin B)

Defence; inhibition of casein kinase II

31J

-0.6444

BC066901

H3 histone, family 3B (H3.3B)

Chromatin remodelling

5AK

-0.6394

BC034149

Ribosomal protein S3

Ribosome production

23V

0.639

AK026634

Highly similar to HUMTI227HC, mRNA for TI-227H

-

21AH

0.627

BC047681

S100 calcium binding protein A9 (Calgranulin B)

Defence; inhibition of casein kinase II

24AQ

-0.627

BC001126

Ribosomal protein S14

Ribosome production

28T

0.6231

NM_000980

Ribosomal protein L18a

Ribosome production

31AF

0.6215

AY495316

Cytochrome c oxidase subunit, COX 1

Mitochondrial electron transport chain

15AK

0.6112

NM_001016

Ribosomal protein S12

Ribosome production

22S

0.6102

-

-

-

20AG

0.5839

BC016378

Ribosomal protein S11

Ribosome production

8S

0.5827

AY495316

Cytochrome c oxidase subunit, COX 1

Mitochondrial electron transport chain

27AG

0.5729

AF077043

Ribosomal protein L36

Ribosome production

3AR

0.5699

AF346981

Mitochondrial 16S rRNA

Ribosome production

25P

0.5507

BC013857

H3 histone, family 3A

Chromatin remodelling

3T

-0.5496

M22146

Ribosomal protein S4

Ribosome production

31U

0.5176

BC016857

Ferritin, heavy polypeptide 1

Iron storage; defence against ROS

6N

-0.5134

BC053370

Ribosomal protein SA

Ribosome production

2G

0.5113

BC010165

Ribosomal protein S2

Ribosome production

2V

0.5071

BC009689

Cyclin D-type binding protein

E2F-mediated transcription

21O

0.4978

BC018641

Eukaryotic translation elongation factor 1α (eEF1A)

Protein translation

4AA

0.4974

D87735

Ribosomal protein L14

Ribosome production

19H

0.486

-

-

-

6AQ

0.4837

BC016857

Ferritin, heavy polypeptide 1

Iron storage; defence against ROS

3AB

-0.481

BC012146

Ribosomal protein L3

Ribosome production

32AM

0.4776

BC001126

Ribosomal protein S14

Ribosome production

25R

0.4759

BC006784

Ribosomal protein S14

Ribosome production

24AJ

0.4695

J03223

Human secretory granule proteoglycan peptide core

Defence (may neutralize hydrolytic enzymes)

11H

-0.4681

AY147037

Myeloid/lymphoid or mixed-lineage leukemia 5 cDNA

Chromatin remodeling and cellular growth suppression

30AP

0.4669

CD246392, EST

Agencourt_14095501 NIH_MGC_172 cDNA

-

8AK

0.4666

AY339570

Cytochrome c oxidase subunit, COX 1

Mitochondrial electron transport chain

2E

0.4662

U43701

Human ribosomal protein L23a

Ribosome production

8G

0.4629

AY495252

Mitochondrial 16S rRNA

Ribosome production

8AF

0.4625

  1. The position of genes in the array is shown as well as their scores, the accession number of sequences in public databases that match them, and their known or putative cellular function. aThe score is a shrunken t-statistic for comparing breast-cancer class to non-breast-cancer class. A positive score means that expression was greater in the noncancer sample than the cancer sample; a negative score means that expression was greater in the cancer sample than the noncancer sample. -, no information available; ROS, reactive oxygen species.
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Breast Cancer Research

ISSN: 1465-542X

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