Table 5 Association of progesterone receptor status and reproductive and family history variables
Reproductive and family history characteristics | PgR-positive or borderline tumors (n = 91) | PgR-negative tumors (n = 85) | ORa | 95% CI | P |
|---|---|---|---|---|---|
Age at menarche (years)b | |||||
<12 | 14 (15.6) | 21 (25.3) | 1.0 (ref) | ||
≥ 12 | 76 (84.4) | 62 (74.7) | 0.6 | 0.3–1.2 | 0.14 |
Age at first full-term pregnancy | |||||
No full-term pregnancies | 27 (29.7) | 25 (29.4) | 1.0 (ref) | ||
<20 | 10 (11.0) | 15 (17.6) | 1.6 | 0.6–4.4 | 0.37 |
20–24 | 25 (27.5) | 20 (23.5) | 0.8 | 0.4–2.0 | 0.71 |
25–29 | 19 (20.9) | 18 (21.2) | 1.1 | 0.5–2.6 | 0.82 |
30–34 | 10 (11.0) | 7 (8.2) | 0.9 | 0.3–2.9 | 0.88 |
Trend | 0.65 | ||||
Total live births | |||||
0 | 27 (29.7) | 25 (29.4) | 1.0 (ref) | ||
1–2 | 53 (58.2) | 50 (58.8) | 1.1 | 0.5–2.1 | 0.87 |
3 or more | 11 (12.1) | 10 (11.8) | 1.0 | 0.3–2.9 | 1.00 |
Trend | 0.95 | ||||
Total miscarriages (gravid women) | |||||
0 | 54 (76.1) | 45 (69.2) | 1.0 (ref) | ||
1 or more | 17 (23.9) | 20 (30.8) | 1.4 | 0.7–3.0 | 0.38 |
Total induced abortions (gravid women) | |||||
0 | 46 (64.8) | 44 (67.7) | 1.0 (ref) | ||
1 or more | 25 (35.2) | 21 (32.3) | 0.8 | 0.4–1.7 | 0.65 |
Breastfeeding (parous women) | |||||
Never | 14 (21.9) | 25 (41.7) | 1.0 (ref) | ||
Ever | 50 (78.1) | 35 (58.3) | 0.4 | 0.2–0.8 | 0.02 |
Months between last full-term pregnancy and diagnosis | |||||
No full-term pregnancy | 27 (29.7) | 25 (29.4) | 1.0 (ref) | ||
0–23 | 17 (18.7) | 16 (18.8) | 1.0 | 0.4–2.5 | 0.95 |
≥ 24 | 47 (51.6) | 44 (51.8) | 1.1 | 0.5–2.2 | 0.87 |
Trend | 0.87 | ||||
Oral contraceptive use | |||||
Never | 19 (20.9) | 10 (11.8) | 1.0 (ref) | ||
Ever | 72 (79.1) | 75 (88.2) | 2.0 | 0.8–4.6 | 0.11 |
Total months of oral contraceptive usec | |||||
None | 19 (21.3) | 10 (12.2) | 1.0 (ref) | ||
1–35 | 23 (25.8) | 23 (28.0) | 1.6 | 0.6–3.9 | 0.33 |
36–83 | 14 (15.7) | 20 (24.4) | 2.3 | 0.9–6.1 | 0.10 |
84 or more | 33 (37.1) | 29 (35.4) | 1.5 | 0.6–3.5 | 0.38 |
Trend | 0.34 | ||||
Family history of breast or ovarian cancerd | |||||
No family history | 71 (78.9) | 70 (83.3) | 1.0 (ref) | ||
Mother or sister | 19 (21.1) | 14 (16.7) | 0.8 | 0.4–1.8 | 0.58 |