Table 2 Association of stage of breast cancer diagnosis and reproductive and family history variables
Reproductive and family history characteristics | Localized (n = 131) | Nonlocalized (n = 116) | ORa | 95% CI | P |
|---|---|---|---|---|---|
Age at menarche (years)b | |||||
<12 | 26 (19.8) | 29 (25.4) | 1.0 (ref) | ||
≥ 12 | 105 (80.2) | 85 (74.6) | 0.8 | 0.4–1.4 | 0.35 |
Age at first full-term pregnancy (years) | |||||
No full-term pregnancies | 48 (36.6) | 29 (25.0) | 1.0 (ref) | ||
<20 | 12 (9.2) | 19 (16.4) | 3.0 | 1.2–7.4 | 0.02 |
20–24 | 31 (23.7) | 35 (30.2) | 2.1 | 1.0–4.3 | 0.04 |
25–29 | 25 (19.1) | 24 (20.7) | 1.7 | 0.8–3.6 | 0.15 |
30–34 | 15 (11.4) | 9 (7.8) | 1.1 | 0.4–2.9 | 0.86 |
Trend | <0.01 | ||||
Total live births | |||||
0 | 48 (36.6) | 29 (25.0) | 1.0 (ref) | ||
1–2 | 71 (54.2) | 67 (57.8) | 1.7 | 0.9–3.1 | 0.07 |
3 or more | 12 (9.2) | 20 (17.2) | 3.1 | 1.3–7.7 | 0.01 |
Trend | 0.01 | ||||
Total miscarriages (gravid women) | |||||
0 | 69 (74.2) | 67 (72.0) | 1.0 (ref) | ||
1 or more | 24 (25.8) | 26 (28.0) | 1.2 | 0.6–2.3 | 0.59 |
Total induced abortions (gravid women) | |||||
0 | 65 (69.9) | 59 (63.4) | 1.0 (ref) | ||
1 or more | 28 (30.1) | 34 (36.6) | 1.2 | 0.7–2.3 | 0.51 |
Breastfeeding (parous women) | |||||
Never | 25 (30.1) | 26 (29.9) | 1.0 (ref) | ||
Ever | 58 (69.9) | 61 (70.1) | 1.1 | 0.5–2.2 | 0.80 |
Months between last full-term pregnancy and diagnosis | |||||
No full-term pregnancy | 48 (36.6) | 29 (25.0) | 1.0 (ref) | ||
0–23 | 23 (17.6) | 26 (22.4) | 1.9 | 0.9–3.9 | 0.09 |
24 or more | 60 (45.8) | 61 (52.6) | 1.9 | 1.0–3.5 | 0.05 |
Trend | 0.06 | ||||
Oral contraceptive use | |||||
Never | 19 (14.5) | 21 (18.1) | 1.0 (ref) | ||
Ever | 112 (85.5) | 95 (81.9) | 0.8 | 0.4–1.5 | 0.43 |
Total months of oral contraceptive usec | |||||
None | 19 (14.6) | 21 (18.9) | 1.0 (ref) | ||
1–35 | 35 (26.9) | 29 (26.1) | 0.6 | 0.3–1.3 | 0.22 |
36–83 | 33 (25.4) | 29 (26.1) | 0.7 | 0.3–1.4 | 0.30 |
84 or more | 43 (33.1) | 32 (28.8) | 0.6 | 0.3–1.2 | 0.17 |
Trend | 0.46 | ||||
Family history of breast or ovarian cancerd | |||||
No family history | 109 (83.8) | 95 (82.6) | 1.0 (ref) | ||
Mother or sister | 21 (16.2) | 20 (17.4) | 1.2 | 0.6–2.3 | 0.67 |