Benign breast disease, recent alcohol consumption, and risk of breast cancer: a nested case–control study

Breast Cancer Research

Table 3 Effect of category of benign breast disease histology on breast cancer risk^a

Benign breast disease category	Cases No. (%)	Controls No. (%)	OR (95% CI)^b	OR (95% CI)^c
Nonproliferative	69(24.5)	474 (38.8)	1.00 (Ref)	1.00 (Ref)
Proliferative without atypia	140 (49.7)	623 (50.9)	1.59 (1.16–2.18)	1.54 (1.12–2.11)
Atypical hyperplasia	73 (25.9)	126 (10.3)	4.54 (3.03–6.78)	4.43 (2.93–6.69)
Total	282	1,223

^aNurses' Health Study I (1976 to 1994) and II (1989 to 1995). ^bAdjusted for age, year of biopsy, and follow-up interval. ^cAdjusted for age, year of biopsy, and follow-up interval, age at menarche, body mass index, weight change since age 18, age at first birth/parity, menopausal status/type of menopause, duration of postmenopausal hormone use. CI, confidence interval; OR, odds ratio; Ref, reference group for statistical comparisons.

ISSN: 1465-542X