|
Benign breast disease category
|
Cases No. (%)
|
Controls No. (%)
|
OR (95% CI)b
|
OR (95% CI)c
|
|---|
|
Nonproliferative
|
69(24.5)
|
474 (38.8)
|
1.00 (Ref)
|
1.00 (Ref)
|
|
Proliferative without atypia
|
140 (49.7)
|
623 (50.9)
|
1.59 (1.16–2.18)
|
1.54 (1.12–2.11)
|
|
Atypical hyperplasia
|
73 (25.9)
|
126 (10.3)
|
4.54 (3.03–6.78)
|
4.43 (2.93–6.69)
|
|
Total
|
282
|
1,223
| | |
-
aNurses' Health Study I (1976 to 1994) and II (1989 to 1995). bAdjusted for age, year of biopsy, and follow-up interval. cAdjusted for age, year of biopsy, and follow-up interval, age at menarche, body mass index, weight change since age 18, age at first birth/parity, menopausal status/type of menopause, duration of postmenopausal hormone use. CI, confidence interval; OR, odds ratio; Ref, reference group for statistical comparisons.
