Effects of milk fermented by Lactobacillus helveticusR389 on a murine breast cancer model

Breast Cancer Research

Table 1 Cytokine-positive cells isolated from the tumour

Experimental group	Sample (days)	Cytokine
		Tumour necrosis factor alpha	Interferon gamma	IL-6	IL-4	IL-10
Tumour control	18	24 ± 2^ae	22 ± 6^ac	29 ± 2^a	25 ± 5^a	18 ± 2^ae
	22	12 ± 4^bcd	17 ± 3^ad	25 ± 3^a	17 ± 4^ad	6 ± 2^b
	27	13 ± 1^bcd	12 ± 4^b	23 ± 4^abd	10 ± 3^ce	8 ± 2^b
P(+) 2d	18	21 ± 3^ce	26 ± 8^cde	12 ± 3^d	11 ± 1^bcde	19 ± 4^a
	22	9 ± 1^d	10 ± 2^b	8 ± 1^cd	12 ± 2^bcde	7 ± 3^bc
	27	11 ± 3^bd	12 ± 4^bd	17 ± 3^d	10 ± 1^ce	9 ± 2^bc
P(-) 2d	18	14 ± 6^bcd	14 ± 5^abd	10 ± 3^c	7 ± 2^e	9 ± 4^bc
	22	19 ± 4^bce	13 ± 4^ab	16 ± 1^bd	13 ± 5^bcde	18 ± 6^ae
	27	12 ± 2^bd	12 ± 2^b	17 ± 2^bd	7 ± 2^e	8 ± 2^bd
P(+) 7d	18	22 ± 7^ac	20 ± 2^ae	4 ± 2^c	15 ± 5^dbc	14 ± 3^ace
	22	31 ± 4^a	30 ± 5^c	9 ± 2^c	8 ± 1^e	29 ± 7
	27	13 ± 1^bcd	17 ± 5^abe	4 ± 1^c	6 ± 1^e	12 ± 2^eb
P(-) 7d	18	12 ± 2^bcd	14 ± 1^b	4 ± 1^c	12 ± 3^bcde	13 ± 6^acde
	22	53 ± 15	44 ± 6	17 ± 3^bd	12 ± 3^bcde	16 ± 4^ace
	27	11 ± 4^bd	24 ± 5^ac	13 ± 4^d	9 ± 1^ce	9 ± 3^bcd

Results are expressed as means ± standard deviation of cytokine-positive cells for each 100 counted cells (cells/100). Means for each cytokine without a common letter differ significantly (P < 0.05).

ISSN: 1465-542X