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Table 1 Comparison of demographic characteristics and potential risk factors for breast cancer in two study populations

From: CYP17 5'-UTR MspA1 polymorphism and the risk of premenopausal breast cancer in a German population-based case–control study

Population statistics and characteristics

Present study population

Original study populationa

 

Cases (n = 527)

Controls (n = 904)

Cases (n = 706)

Controls (n = 1,381)

Mean age (years) at diagnosis or recruitment

41.6

41.7

42.5

42.6

Mean BMI (kg/m2)

24.0

23.9

24.1

24.2

Mean age (years) at menarche

13.1

13.1

13.1

13.1

Mean age (years) at first full-term pregnancyb

24.4

24.9

24.2

24.3

Population characteristics (%)

   Study region

    

Rhein–Neckar–Odenwald

71.7

70.7

70.0

69.3

Freiburg

28.3

29.3

30.0

30.7

   Marital statusc

    

Single

9.3

9.8

7.8

8.4

Married/with partner

81.0

80.0

81.2

78.3

Widowed, divorced or separated

9.7

10.2

10.9

13.2

   Nationality

    

German

91.8

97.0

91.2

95.8

Non-German

8.2

3.0

8.8

4.2

   Educational level

    

Low

13.5

11.7

14.7

14.2

Intermediate

63.7

60.7

63.3

60.3

High

22.8

27.6

22.0

25.5

   Parity

    

0

23.5

22.0

21.7

20.8

1

27.7

24.1

29.0

24.5

2

39.5

37.5

38.5

38.0

3+

9.3

16.4

10.8

16.7

   Oral contraceptive used

    

No

16.1

19.7

18.1

19.8

Yes

83.9

80.1

81.9

80.0

   Breastfeedingb

    

Never

28.8

26.5

31.3

29.2

Ever

71.2

73.5

68.7

70.8

   First-degree family history of breast cancer

    

No

87.7

94.7

87.7

94.9

Yes

12.3

5.3

12.3

5.1

   Daily average alcohol intake

    

   0 g

20.7

16.4

21.7

17.3

   1–18 g

65.6

74.5

63.8

74.1

   >18 g

13.7

9.1

14.5

8.7

  1. aAll who completed questionnaires. bLimited to parous women. cTwo controls from the original study population had unknown marital status. dThree controls from the original study and two controls from the present study have missing data. BMI, body mass index.