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Table 1 Mammary fat pad model tumor take and metastasis

From: Bioluminescent human breast cancer cell lines that permit rapid and sensitive in vivodetection of mammary tumors and multiple metastases in immune deficient mice

Cell line Experimental parameters Detected metastases
  Mouse strain n Take rate End-point (weeks) LN in vivo Lung ex vivo
D3H1 Nude 9, 10 40–78% 8–13 75–86% R, 0% L 0–16%
  Nude-beige 6 66% 13 67% R, 16% L 0%
D3H2LN Nude 9, 8 89–100% 5 100% R, 0% L 38%
  Nude-beige 8 75% 9 100% R, 100% L 67%
  1. L, left; LN, lymph node; R, right.