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Table 1 Mammary fat pad model tumor take and metastasis

From: Bioluminescent human breast cancer cell lines that permit rapid and sensitive in vivodetection of mammary tumors and multiple metastases in immune deficient mice

Cell line

Experimental parameters

Detected metastases

 

Mouse strain

n

Take rate

End-point (weeks)

LN in vivo

Lung ex vivo

D3H1

Nude

9, 10

40–78%

8–13

75–86% R, 0% L

0–16%

 

Nude-beige

6

66%

13

67% R, 16% L

0%

D3H2LN

Nude

9, 8

89–100%

5

100% R, 0% L

38%

 

Nude-beige

8

75%

9

100% R, 100% L

67%

  1. L, left; LN, lymph node; R, right.
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Breast Cancer Research

ISSN: 1465-542X

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