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Figure 5 | Breast Cancer Research

Figure 5

From: Mammary stem cells, self-renewal pathways, and carcinogenesis

Figure 5

A hypothetic interacting model in the regulation of stem cell self-renewal by the Hedgehog signaling pathway, the Notch signaling pathway, the Wnt signaling pathway, and B lymphoma Mo-MLV insertion region 1 (Bmi-1). Interactions between the Hedgehog, Notch, and Wnt pathways and Bmi-1 are shown by solid arrows; interactions between stem cell self-renewal regulation by the pathways and Bmi-1 are shown by dashed arrows; the question marks represent the postulated interactions.

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