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Table 1 Characteristics of invasive breast cancer cases and population controls, Wisconsin, 2001 to 2003

From: A case-control study of the HER2 Ile655Val polymorphism in relation to risk of invasive breast cancer

Characteristic Cases (N = 1,094) Controls (N = 976) OR 95% CI
  n % n %*   
Family history of breast cancer       
   Absent 855 78.2 829 85.3 1 (Reference)
   Present 231 21.1 132 13.1 1.69 1.33–2.16
   Unknown 8 0.7 15 1.7 0.44 0.18–1.05
Recent alcohol consumption       
   None 153 14.0 166 16.8 1 (Reference)
   1 drink/week 424 38.8 418 42.5 1.10 0.84–1.45
   2–6 drinks/week 385 35.2 270 28.2 1.57 1.19–2.09
   7 or more drinks/week 132 12.1 122 12.4 1.23 0.87–1.74
Parity       
   0–1 262 23.9 217 23.4 1 (Reference)
   2 392 35.8 275 29.7 1.22 0.95–1.55
   3 253 23.1 209 21.3 0.99 0.76–1.30
   4 or more 187 17.1 275 25.6 0.58 0.44–0.77
Menopausal status       
   Postmenopausal 597 54.6 592 55.1 1 (Reference)
   Premenopausal 415 37.9 313 36.8 1.25 0.92–1.70
   Unknown 82 7.5 71 8.1 1.06 0.71–1.58
Age at menopause (years)       
   <45 138 23.1 175 30.1 1 (Reference)
   45–49 113 18.9 127 21.4 1.15 0.80–1.65
   50–54 205 34.3 172 29.0 1.61 1.16–2.23
   55+ 68 11.4 65 10.1 1.42 0.91–2.20
   Unknown 73 12.2 53 9.4 1.76 1.14–2.77
Body mass index (kg/m2)       
   <22.6 129 21.6 135 23.1 1 (Reference)
   22.6–25.2 144 24.1 136 22.8 1.18 0.82–1.69
   25.3–28.9 166 27.8 161 26.8 1.09 0.77–1.54
   29.0+ 153 25.6 156 26.6 0.97 0.69–1.38
Weight change since age 18 (kg)       
   Lost 5 or more 14 2.3 20 3.5 0.92 0.42–2.03
   Lost 5 to gained 4 95 15.9 109 18.9 1 (Reference)
   Gained 5 to 11 148 24.8 140 23.3 1.42 0.97–2.09
   Gained 12 to 21 179 30.0 172 28.7 1.30 0.90–1.88
   Gained 22 or more 154 25.8 143 24.3 1.32 0.91–1.93
HRT use       
   Never 184 30.8 233 37.9 1 (Reference)
   Former 45 7.5 77 12.6 0.65 0.42–1.01
   Current 368 61.6 282 49.4 1.49 1.14–1.95
Age at menarche (years)       
   < 12 228 20.8 176 18.1 1 (Reference)
   12 282 25.8 253 26.4 0.83 0.64–1.09
   13 297 27.1 244 24.4 0.94 0.72–1.23
   14 183 16.7 172 17.6 0.81 0.61–1.10
   15+ 98 9.0 119 12.4 0.63 0.45–0.89
Height at age 25 (m)       
   < 1.60 198 18.1 218 21.9 1 (Reference)
   1.60–1.64 295 27.0 263 27.0 1.25 0.96–1.62
   1.65–1.67 299 27.3 264 26.9 1.26 0.97–1.64
   1.68+ 302 27.6 231 24.1 1.47 1.12–1.92
  1. *Control percentages are age-adjusted to the distribution of cases; logistic regression models conditional on age; among postmenopausal women. CI, confidence interval; HRT, hormone replacement therapy; OR, odds ratio.