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Table 4 Phenotype of DC-Tuper stimulated lymphocytes

From: Dendritic cells are defective in breast cancer patients: a potential role for polyamine in this immunodeficiency

Phenotype (%)

Donor

Breast cancer

 

NSL

NSL + DC-Tuper

NSL

NSL + DC-Tuper

CD3+CD56-

73 ± 30

76 ± 24

75 ± 17

73 ± 15

CD3-CD56+

6 + 8

5 ± 6

10 ± 13

5 ± 5

CD3+CD56+

18 ± 21

18 ± 18

11 ± 5

20 ± 13

CD4+ T cell

28 ± 30

24 ± 27

29 ± 21

31 ± 22

CD8+ T cell

51 ± 21

57 ± 18

51 ± 19

59 ± 18

TCR α/β

75 ± 23

77 ± 23

70 ± 20

83 ± 12

TCR γ/δ

14 ± 15

13 ± 18

14 ± 11

11 ± 12

  1. Cells are from healthy donors (n = 3) or breast cancer patients (n = 6). The percentage of positive cells for lymphocyte markers was measured in a 99% CD45+ population. Data are expressed as mean ± standard deviation. DC-Tu, dendritic cells pulsed with treated tumour cells; NSL, nonstimulated lymphocytes.